Onyx® LES
The advantage of time, the power of control.
Onyx® is a non-adhesive liquid embolic agent used for the pre-surgical embolization of brain Arteriovenous malformations (bAVM).
- Onyx is comprised of EVOH (ethylene vinyl alcohol) copolymer dissolved in DMSO (dimethyl sulfoxide), and suspended micronized tantalum powder to provide contrast for visualization under fluoroscopy.
- The Onyx Liquid Embolic System (LES™) consists of a 1.5 ml vial of Onyx, a 1.5 ml vial of DMSO, and three 1 ml Onyx delivery syringes.
- A DMSO compatible delivery micro catheter that is indicated for use in the neuro vasculature (e.g. Marathon™, Rebar™ or UltraFlow™ HPC catheters) is used to access the embolization site.
- Onyx is available in two product formulations, Onyx 18 (6% EVOH) and Onyx 34 (8% EVOH).

- Onyx 18 will travel more distally and penetrate deeper into the nidus due to its lower viscosity compared to Onyx 34.
- Final solidification occurs within five minutes for both product formulations.
For additional product information please contact your regional sales representative.
Onyx LES is intended for the embolization of lesions in the peripheral and neurovasculature, including arteriovenous malformations and hypervascular tumors. Onyx Aneurysm System is indicated for use in the embolization of intracranial aneurysms.
Indications, Contraindications, warnings and instructions for use can be found in the product labeling supplied with each device.